"Cocaine enhances the response of the innervated structures of the sympathetic system, as well as adrenaline and norepinephrine (sympathetic chemical transmitters)

. In this way, they provoke vessel constriction, mydriasis and tachycardia (sympatho-mimetic action.)"

The action mechanism of cocaine as a stimulant is based on the blocking of the recapture of norepinephrine in the inter-synaptic gap.